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Background: Currently, COVID-19 is a global public health problem. This study aimed to estimate the seroprevalence of antibodies related to Covid-19 in the general population in southern Iran. Methods: This cross-sectional population-based study of the seroepidemiological type investigated the serological prevalence of COVID-19 from October to December 2020 in Jahrom, Fars province, Iran. A total of 612 participants were selected using multistage cluster random sampling regardless of age or gender. The dataset in the study included the participants' demographic information, the history of exposure to COVID-19 patients, the history of PCR tests, and the history of COVID-19 symptoms in previous months. In addition, this study examined the raw and survey-weight adjusted estimates with Stata version 14. Finally, logistic regression was performed to identify risk factors for serum prevalence. Results: The participants' mean age was 38.88±13.91 and the majority were 30 to 49 years (51.4%), with a female preponderance (58.7%). The estimated adjusted seroprevalence was 32.66 (95%CI: 28.93-36.63), with 207 positive cases for either IgG or IgM. The results of multivariable logistic regression showed that seropositivity in the participants was 4.95 times more likely associated with a history of positive PCR test (OR: 4.95, 95%CI: 2.46-10.90) and 2.14 times in patients with a history of muscle pain in previous months (OR: 2.14, 95%CI: 1.03-4.47). Conclusion: The actual number of patients with COVID-19 is significantly higher than the number of cases confirmed by the disease monitoring system based on PCR tests. Therefore, tracking individuals' contact with confirmed patients using extensive testing and segregation of asymptomatic patients can help control the epidemic. © Journal of Health Sciences and Surveillance System. All rights reserved.
RESUMEN
A novel coronavirus 2019 (Covid-19) was identified in Wuhan, China causing an outbreak of pneumonia worldwide. The first infection of the coronavirus was associated with a kind of seafood. The patient of the covid-19 pandemic was accompanied by the most common symptoms of fever, lung inflammation, dry cough, and tiredness. Researchers have found that natural flavonoid and antioxidant products such as wildly phytomedicine and anti-inflammatory drugs can play a therapeutically rolls in accelerating the recovery of the viral disease. Fisetin, a known flavonoid in fruits and vegetables, is a powerful anti-inflammatory and antioxidant. With the help of drug delivery technology, fisetin can be present in nanoparticles in a targeted manner in a short time with the minimum dose and also the least side effects to create a high degree of effectiveness in the treatment of this virus.
RESUMEN
Coronaviruses infected different species of animals, such as feline, canine, swine and bovine. In veterinary medicine, a significant fatal coronavirus disease in Felidae is Feline Infectious Peritonitis (FIP). The Internet provided many websites about small animals that present educational content for disease prevention, pets welfare, etc. Upper than 90% of internet users chooses Google as a search engine. In 2008, Google Company launched Google Insights for search that displaying search trends data. Finally, this company merged Google Insights for Search into Google Trends (GT).We conducted a Google Trends analysis to evaluate search interest in FIP and feline coronavirus in the COVID-19 pandemic. For this purpose, we search two topics, "Feline infectious peritonitis" and "Feline coronavirus” in GT, for collecting data. The duration of study was selected in two periods: January-November 2020, the COVID-19 period and the same period in 2019 for comparison. Comparison of the RSV means between these two periods was performed using two independent samples t-test with assuming unequal variances and two-sided p-value <0.05 considered statistically significant. The RSV of "Feline infectious peritonitis" and "Feline coronavirus" topics have significantly increased during the COVID-19 period comparing with the same period in 2019 (p-value <0.05). After the COVID-19 pandemic onset, all aspects of our lives were affected by pandemic consequent problems. This global attention to COVID-19 has made a valuable opportunity for presenting the importance of corona viral diseases in any species. The increase of interest in searching about Feline infectious peritonitis and Feline coronavirus indicated that continued global concerns were raised about this infection in felines. The results of this study can be useful for animal health policymakers, veterinarians and journalists to help reduce concerns about FIP and Feline coronavirus by providing educational content on the Internet. © 2021 Mohammad Jokar, Vahid Rahmanian, Nader Sharifi, Narges Rahmanian and Hekmatollah Khoubfekr.